Gene information
Official symbol CCR2
Official full name C-C motif chemokine receptor 2
Gene type protein-coding gene
Chromosome3p21.31
Alias symbolCC-CKR-2; CKR2; MCP-1-R; CD192; FLJ78302
Previous symbolCMKBR2
Gene familyCD molecules; C-C motif chemokine receptors
Resources
Entrez Gene 729230
HGNC HGNC:1603
Ensembl ENSG00000121807
Vega OTTHUMG00000156466
UCSC uc003cpn.5
GO terms: 29 records
GO Description Category LogP Number of genes Detail
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002695 negative regulation of leukocyte activation GO Biological Processes -9.84552767 31 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032412 regulation of ion transmembrane transporter activity GO Biological Processes -9.90560995 38 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0050777 negative regulation of immune response GO Biological Processes -11.1440698 32 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0050806 positive regulation of synaptic transmission GO Biological Processes -4.32260958 18 More
GO:0050866 negative regulation of cell activation GO Biological Processes -13.9027363 39 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
GO:2001257 regulation of cation channel activity GO Biological Processes -11.2578208 33 More
Drug-Gene interaction
view
Related drugs: 11 records
Drug name Interaction type Source PMID View
azd2423 allosteric modulatorantagonist ChemblInteractionsTTD view
ccx140 antagonist TdgClinicalTrialChemblInteractionsTTD view
cenicriviroc antagonist ChemblInteractionsTTD view
chembl41275 antagonist DTC 17715128 view
mk-0812 TTD view
morphine NCI 16831471 view
pf-04634817 antagonist ChemblInteractions view
pimagedine TTD view
plerixafor DTC 17715128 view
plozalizumab antagonistantibody TdgClinicalTrialChemblInteractions view
simvastatin NCI 15781755 view
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
NM_001123396.4:c.190G>A genomics myocardial infarction[diagnosis] myocardial infarction Petrkova J et al. Immunol Lett. 2003
NM_001123396.4:c.190G>A genomics myocardial infarction[diagnosis] myocardial infarction Ortlepp JR et al. Int J Cardiol. 2005
NC_000003.12:g.[46357717G>A;46373456_46373487del] genomics myocardial infarction[diagnosis] myocardial infarction Kallel A et al. Clin Biochem. 2012
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